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1d and 2d nmr spectra processing  (Bruker Corporation)


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    Structured Review

    Bruker Corporation 1d and 2d nmr spectra processing
    1d And 2d Nmr Spectra Processing, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/2d+spectra+processing/d8+advance+diffractometer/pm39373871-45-10-16
    Average 90 stars, based on 1 article reviews
    1d and 2d nmr spectra processing - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: Epigallocatechin Gallate with Potent Anti- Helicobacter pylori Activity Binds Efficiently to Its Histone-like DNA Binding Protein
    Article Snippet: The acquired FID signals in the 2D array format were then processed using Bruker command ≪xf2≫ (other processing parameters were identical to those used for processing ZGESGP spectra).

    Article Title: Resolution improvement of solid-state two-dimensional 23Na nutation NMR spectra by magic angle spinning
    Article Snippet: Application of magic angle spinning of small spherical volumes of powder samples at high magnetic field strength B,,, high power rf irradiation, and careful data processing including resolution enhancement leads to highly resolved two-dimensional 23Na nutation NMR spectra of aluminosilicate sodalites containing different enclalhrated sodium salts.. Up to six lines have been resolved in the F, dimension with minimum shift differences of less than 3 ppm.. Qualitative information on the quadrupole interaction of the corresponding sodium sites has been derived from the nutation line shape in the F, dimension.

    Nuclear Magnetic Resonance:

    Article Title: Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure.
    Article Snippet: Cyclic peptides have gained a lot of interest over the last 20 years in applied and academic drug discovery research owing to their rediscovered potential as therapeutics.. In contrast to their linear counterparts, they have a restricted conformation, increased proteolytic stability, decreased polarity by eliminating charged termini, and higher propensity for internal hydrogen bonding, all of which result in improved drug-like properties.. However, it is the high affinity and selectivity that many representatives of this class of cyclic compounds exhibit, even against difficult targets, that make them so attractive.

    Article Title: NMR-derived model of interconverting conformations of an ICAM-1 inhibitory cyclic nonapeptide.
    Article Snippet: We have produced by phage-display a disulfide-linked cyclic nonapeptide (inhibitory peptide-01, IP01), CLLRMRSIC, that binds to intracellular adhesion molecule-1 (ICAM-1) and blocks binding to its counter-structure, leukocyte functional antigen-1 (LFA-1).. As a first step towards improving its pharmacologic properties, we have performed a structural and functional analysis of this peptide inhibitor to determine the features relevant to ICAM-1 binding.. We report here the solution model of our initial product, IP01, as derived from two-dimensional nuclear magnetic resonance (NMR) restraints and molecular modeling.

    Diffusion-based Assay:

    Article Title: Ligand-Induced Protein Mobility in Complexes of Carbonic Anhydrase II and Benzenesulfonamides with Oligoglycine Chains
    Article Snippet: .. The 1 H spectra were analyzed using the standard 2D DOSY processing protocol in the Topspin 2.1 (Bruker) software package to obtain the DOSY spectra ( ) from which diffusion coefficients of the SA-Gly n ligands were extracted. .. Amide hydrogen/deuterium exchange studies were performed as previously described , using a Thermo-Finnigan LTQ Ion Trap ESI-MS.



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